Histochemical and Ultrastructural Observation of the Pigment in Pigmented Lipid Histiocytes
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چکیده
Chronic granulomatous disease (CGD) results from a congenital bactericidal defect within phagocytic cells including neutrophils (3, 9, 17, 18), and has been characterized by the formation of granulomas in generalized organs and by the appearance of histiocytes containing pigmented lipid materials mainly in the reticulo-endothelial system (1, 2). Although one histochemical and ultrastructural report with regard to the yellowish brown pigment of pigmented lipid histiocytes (PLH) has been issued (1), the exact nature of this granule has not yet been examined in detail. In the present study, we focussed mainly on the pigment of PLH, which was found in an autopsy case of CGD (7).
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تاریخ انتشار 2009